Development of a Cancer Diseases Classification Model Using Artificial Intelligence

  • А.А. Шайдуров Altai State University (Barnaul, Russia) Email: shaidurov@phys.asu.ru
  • А.С. Бубликов Altai State University (Barnaul, Russia) Email: madsilver@rambler.ru
Keywords: artificial neural network, a method of confidence intervals, correlation analysis, technology IMMUNOSIGNATURE, oncology, breast cancer

Abstract

The paper deals with the possibility analysis of developing a cancer diseases classification model based on layered artificial neural networks. We studied the data obtained by the IMMUNOSIGNATURE technology. Immunosignaturing requires a drop of test subject blood that contains cells of immune system to be applied to a biochip. The biochip is divided into sectors with unique amino acid sequences. Depending on the intensity of the immune response manifestation in specific cells, a specific profile (signature) is formed for a certain individual. The complexity of immunosignature data analysis lies in external stochastic influence on the obtained results. In the paper, aspects of correlation analysis data correction to get rid of random artifacts are considered. Data normalization procedure to minimize the impact of systemic distortions due to the influence of external factors, such as temperature, humidity, substance concentration, etc., is discussed. Classification is performed by the backpropagation artificial neural network.

DOI 10.14258/izvasu(2015)1.2-32

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Author Biographies

А.А. Шайдуров, Altai State University (Barnaul, Russia)
кандидат технических наук, доцент кафедры вычислительной техники и электроники 
А.С. Бубликов, Altai State University (Barnaul, Russia)
магистрант физико-технического факультета 

References

Alexa K Hughes, Zbigniew Cichacz, Adrienne Scheck, Stephen W. Coons, Stephen Albert Johnston, Phillip Stafford Immuno signaturing Can Detect Products from Molecular Markers in Brain Cancer, 2012, DOI: 10.1371/journal. pone.0040201

Реброва О.Ю. Среднее или все же медиана? // Троицкий вариант. - 2011. - № 90.

Горбань А.Н., Россиев Д.А. Нейронные сети на персональном компьютере. - Новосибирск, 1996.

Золин А.Г, Силаева А.Ю. Применение нейронных сетей в медицине // Актуальные проблемы науки, экономики и образования XXI века : материалы II Междунар. науч.-практ. конф., 5 марта - 26 сентября 2012 года : в 2 ч. Ч. 2 / отв. ред. Е.Н. Шереметьева. - Самара, 2012.

Осовский С. Нейронные сети для обработки информации / пер. с польск. - М., 2004.

How to Cite
Шайдуров А., Бубликов А. Development of a Cancer Diseases Classification Model Using Artificial Intelligence // Izvestiya of Altai State University, 1, № 1/2(85) DOI: 10.14258/izvasu(2015)1.2-32. URL: http://izvestiya.asu.ru/article/view/%282015%291.2-32.